The different setups you can apply depend on the specific workflow you’re in need of - below are some examples: 

1. Configuring your sidechain for your talkback and using the audio track as your input 
   A basic scenario where you would be hearing audio directly from a track (or from a recording session with a talent individual) - you might want to have more control over your talkback microphone by muting/unmuting yourself at specific times without affecting the audio coming from the talent itself - which is particularly handy when there are multiple participants on a call. 
2. Recording videos for voiceover work and using timecode 
   There might be occasions where you want, for example, to work with voiceover videos and lip-sync for animations. In those cases, you usually only want the timecode to go to the camera when you’re recording. Source-Nexus Mute-On can be placed directly on the timecode’s output so that it only hits the camera with timecode when you’re doing a take, and to be muted when you’re playing back the content. 
3. Recording - audio indicators 
   When recording audio, you might want to hear beeps or sounds to indicate when the recording is supposed to start - but you might not want to hear them at all times (when the audio is played back, for example, or when it is stopped). 
4. A simple mute/unmute scenario 
   DAWs don’t provide a way to auto-mute or auto-dim (or to unmute), which is the main advantage of using Source-Nexus Mute-On - applying those changes to each of the different playback states (play, record, stop, or key/MIDI actions).